68
Therapeutic Cloning
question is closely bound up with the principle of division of 
labor the first multicellular organism was probably a cluster 
of similar cells, but these units soon lost their original homo-
geneity: the single cluster would come to be divided into two 
groups of cells, which may be called somatic and reproductive. 
As the complexity of the metazoan body increased, these two 
groups became more sharply separated from each other. Very 
soon the somatic cells surpassed the reproductive in number, 
and during this increase they became more and more broken 
up by the division of labor into sharply separated systems of 
tissues. As these changes took place, the power of reproduc-
ing large parts of the organism was lost, while the power of 
reproducing the whole individual became concentrated in the 
reproductive cells alone. But, it does not therefore follow that 
the somatic cells were compelled to lose the power of unlim-
ited cell reproduction.
So, Weismann made the astonishing prediction that while 
the germ-line cells of multicellular animals, such as humans, 
were  immortal  (specifically,  they  could  replicate  without 
limit), the somatic cells were in fact mortal  that is, they had 
the capacity to divide only a finite number of divisions:
Death takes place because a worn-out tissue cannot for-
ever renew itself, and because a capacity for increase by 
means of cell-division is not everlasting, but finite. [2]
HAYFLICKS EXPERIMENT
In 1961, the cell biologist Leonard Hayflick published the 
seminal work that convinced the scientific community that 
cells in the human body  the somatic cells  are mortal. [3] 
They  could  divide  and  proliferate,  but  as  Weismann  had 
predicted so many years earlier, even with optimum growth